DRUG EVALUATION Leflunomide in juvenile idiopathic arthritis
نویسندگان
چکیده
منابع مشابه
Leflunomide in systemic onset Juvenile idiopathic arthritis.
Methotrexate, the mainstay of treatment in Juvenile idiopathic arthritis, might not be effective in a few patients of polyarticular and systemic onset juvenile idiopathic arthritis. Use of biologicals like TNF-a blockers, the next line of preferred drugs is constrained by the high cost. We successfully used leflunomide in four patients.
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Methods The database of the German Center for Pediatric and Adolescent Rheumatology was searched for all patients admitted from January 2010 until October 2011 with a diagnosis of juvenile idiopathic arthritis and chronic anterior uveitis and treatment periods with both leflunomide and methotrexate. Patients with uveitis due to other causes were excluded. A retrospective chart survey was used t...
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